Anabolic Steroids, Acute Myocardial Infarction And Polycythemia: A Case Report And Evaluation Of The Literature Pmc

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• Other common potential antagonistic results embody infertility, hepatotoxicity, psychological abnormalities, and gynecomastia .
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Rhoden EL, Morgentaler A. Risks of testosterone-replacement remedy and recommendations for monitoring. Testosterone alternative in hypogonadal men with angina improves ischaemic threshold and quality of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone increase human platelet thromboxane A2 receptor density and aggregation responses.

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Erythrocytosis has been reported as a potential effect of testosterone, which may be useful in sufferers with anemia. The best threat of erythrocytosis occurs with injectable types of testosterone in contrast with transdermal preparations, particularly in supraphysiologic doses. An increase of as a lot as 44% of the baseline hematocrit has been reported .

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Anabolic Steroids, Acute Myocardial Infarction And Polycythemia: A Case Report And Review Of The Literature

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We report a case of an acute ST-segment elevation myocardial infarction in a patient with traditional cardiac risk elements using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, probably secondary to high-dose testosterone. The affected person underwent successful percutaneous intervention of the proper coronary artery. Physicians and patients should be aware of the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).